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  • Cell Research
    stem cells Linlin Wang 1 Yan Xue 2 Yihang Shen 2 Wei Li 3 Yan Cheng 2 Xiaoshuang Yan 2 Wansheng Shi 2 Juan Wang 1 Zhijuan Gong 1 Guanheng Yang 1 1 Shanghai Institute of Medical Genetics Shanghai Children s Hospital Shanghai Jiao Tong University Shanghai 200040 China 2 Institute of Medical Science Shanghai Jiao Tong University School of Medicine 280 South Chongqing Road Shanghai 200025 China 3 Institute

    Original URL path: http://www.cell-research.com/arts.asp?id=156 (2016-02-14)
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  • Cell Research

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    Original URL path: /artsmore1.asp?id=12 (2016-02-14)


  • Cell Research
    Izpisua Belmonte 2 3 1 National Laboratory of Biomacromolecules Institute of Biophysics Chinese Academy of Sciences Beijing 100101 China 2 Gene Expression Laboratory Salk Institute for Biological Studies 10010 North Torrey Pines Road La Jolla CA 92037 USA 3 Center for Regenerative Medicine in Barcelona Dr Aiguader 88 08003 Barcelona Spain Correspondence Guang Hui Liua Juan Carlos Izpisua Belmonteb E mail ghliu ibp ac cn belmonte salk edu izpisua cmrb

    Original URL path: http://www.cell-research.com/arts.asp?id=131 (2016-02-14)
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  • Cell Research
    2 1 Institute of Biophysics Chinese Academy of Sciences Beijing 100101 China 2 Laboratory of Immunology National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda MD 20892 1892 USA Correspondence Michael J Lenardo Tel 1 301 496 6754 E mail lenardo nih gov LRRK2 was recently identified as a major susceptibility gene for Crohn s disease CD by genome wide association studies GWAS LRRK2 deficiency in mice

    Original URL path: http://www.cell-research.com/arts.asp?id=132 (2016-02-14)
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  • Cell Research
    St Jude Children s Research Hospital Memphis TN 38105 USA Correspondence Thirumala Devi Kanneganti Tel 1 901 595 3634 E mail Thirumala Devi Kanneganti StJude org Humans can be divided into roughly three groups with distinct microbial communities in their gastro intestinal tract The microbiota contributes to metabolic activity in the gastro intestinal tract of the host but what mechanisms shape the composition of the gut microbiota and how does

    Original URL path: http://www.cell-research.com/arts.asp?id=133 (2016-02-14)
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  • Cell Research
    Science Park Beijing 102206 China Correspondence Feng Shao Tel 86 10 80728593 E mail shaofeng nibs ac cn Intracellular NOD like receptor NLR proteins are believed to play important roles in innate immune detection or immune regulation but only a few NLR proteins are functionally defined Recent intensive studies largely in vitro on NLRC5 reveal multiple and controversial roles of this NLR protein in signaling regulation of both innate and

    Original URL path: http://www.cell-research.com/arts.asp?id=134 (2016-02-14)
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  • Cell Research
    IDH mutations in tumorigenesis Dan Ye 1 Yue Xiong 1 2 4 and Kun Liang Guan 1 3 5 1 Molecular and Cell Biology Laboratory Institutes of Biomedical Sciences Fudan University Shanghai 200032 China 2 College of Life Science Fudan University Shanghai 200032 China 3 College of Medicine Fudan University Shanghai 200032 China 4 Lineberger Comprehensive Cancer Center Department of Biochemistry and Biophysics University of North Carolina at Chapel Hill NC 27599 USA 5 Department of Pharmacology and Moores Cancer Center University of California San Diego La Jolla CA 92093 USA Correspondence Dan Ye Yue Xiong Kun Liang Guan E mail yedan fudan edu cn yxiong email unc edu kuguan ucsd edu Tumor associated mutations in the isocitrate dehydrogenase 1 and 2 IDH1 and IDH2 genes result in the loss of normal catalytic activity the production of α ketoglutarate α KG and gain of a new activity the production of an oncometabolite R 2 hydroxylglutarate R 2 HG New evidence supports previous findings that R 2 HG acts as an antagonist of α KG to competitively inhibit the activity of multiple α KG dependent dioxygenases including both histones and DNA demethylases involved in epigenetic control of gene expression and cell

    Original URL path: http://www.cell-research.com/arts.asp?id=135 (2016-02-14)
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  • Cell Research
    22 ISSUE 7 7 2012 1105 1107 Insights into CRAC channel gating and ion permeation Patrick G Hogan La Jolla Institute for Allergy Immunology 9420 Athena Circle La Jolla CA 92037 USA Correspondence Patrick G Hogan Tel 1 858 952 7175 E mail phogan liai org The ORAI1 store operated calcium channel also known as the CRAC channel has provided many surprises The latest is that channel gating and ion

    Original URL path: http://www.cell-research.com/arts.asp?id=136 (2016-02-14)
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