archive-com.com » COM » C » CELL-RESEARCH.COM

Total: 1754

Choose link from "Titles, links and description words view":

Or switch to "Titles and links view".
  • Cell Research
    2 and Jun Ren 1 2 1 Shanghai Institute of Cardiovascular Diseases Zhongshan Hospital Fudan University Shanghai 200032 China 2 Center for Cardiovascular Research and Alternative Medicine University of Wyoming Laramie WY 82071 USA Correspondence Jun Ren Tel 1 307 766 6131 Fax 1 307 766 2953 E mail jren uwyo edu In a recent paper published in Cell Research an association between expression of mitochondrial aldehyde dehydrogenase ALDH2 a

    Original URL path: http://www.cell-research.com/arts.asp?id=1782 (2016-02-14)
    Open archived version from archive


  • Cell Research
    Neuenheimer Feld 324 69120 Heidelberg Germany 2 Institute of Medical Virology University of Frankfurt Paul Ehrlich Str 40 60596 Frankfurt Germany Correspondence Oliver T Fackler Tel 49 0 6221 561322 Fax 49 0 6221 565003 E mail oliver fackler med uni heidelberg de Oliver T Keppler Tel 49 0 69 6301 5219 Fax 49 0 69 6301 6477 E mail Oliver Keppler kgu de CD4 T lymphocytes represent the main target cell population of human immunodeficiency virus HIV In an activated state CD4 T cells residing in lymphoid organs are a major reservoir of ongoing HIV 1 replication in infected individuals In contrast resting CD4 T cells are highly resistant to productive HIV 1 infection yet are massively depleted during disease progression and represent a substantial latent reservoir for the virus in vivo Barriers preventing replication of HIV 1 in resting CD4 T cells include a rigid layer of cortical actin and early after HIV 1 entry a block that limits reverse transcription of incoming viral RNA genomes Defining the molecular bases of these restrictions has remained one of the central open questions in HIV research Recent advances unraveled mechanisms by which HIV 1 bypasses the entry block and established

    Original URL path: http://www.cell-research.com/arts.asp?id=1783 (2016-02-14)
    Open archived version from archive

  • Cell Research
    1 1 Department of Pharmacology School of Pharmacy Second Military Medical University 325 Guo He Road Shanghai 200433 China 2 Jinan Military General Hospital 25 Shi fan Road Jinan Shandong 250031 China 3 Department of Neurology Xinhua Hospital Shanghai Jiaotong University 1665 Kongjiang Road Shanghai 200092 China 4 Department of Cardiology Chaoyang Hospital Capital Medical University 8th Gongtinanlu Road Chaoyang District Beijing 100020 China 5 Department of Neurology Changhai Hospital Second Military Medical University 174 Changhai Road Shanghai 200433 China 6 Department of Gerontology Xinhua Hospital Shanghai Jiaotong University 1665 Kongjiang Road Shanghai 200092 China 7 Division of Cardiology University of Arkansas for Medical Sciences and the Central Arkansas Veterans Healthcare System Little Rock AR USA These two authors contributed equally to this work Correspondence Ai Jun Liu E mail mrliuaijun 163 com Ding Feng Su Tel and Fax 86 21 65493951 E mail dfsu2008 gmail com Aldehyde dehydrogenase 2 ALDH2 is a mitochondrial enzyme that metabolizes ethanol and toxic aldehydes such as 4 hydroxy 2 nonenal 4 HNE Using an unbiased proteomic search we identified ALDH2 deficiency in stroke prone spontaneously hypertensive rats SHR SP as compared with spontaneously hypertensive rats SHR We concluded the causative role of ALDH2 deficiency in neuronal injury as overexpression or activation of ALDH2 conferred neuroprotection by clearing 4 HNE in in vitro studies Further ALDH2 knockdown rats revealed the absence of neuroprotective effects of PKCε Moderate ethanol administration that is known to exert protection against stroke was shown to enhance the detoxification of 4 HNE and to protect against ischemic cerebral injury through the PKCε ALDH2 pathway In SHR SP serum 4 HNE level was persistently elevated and correlated inversely with the lifespan The role of 4 HNE in stroke in humans was also suggested by persistent elevation of its plasma levels for

    Original URL path: http://www.cell-research.com/arts.asp?id=1784 (2016-02-14)
    Open archived version from archive

  • Cell Research
    during CNS myelination in vivo Peng Liu 1 Jiu lin Du 2 and Cheng He 1 1 Department of Neurobiology and Key Laboratory of Molecular Neurobiology of Ministry of Education Second Military Medical University 800 Xiangyin Road Shanghai 200433 China 2 Institute of Neuroscience and State Key Laboratory of Neuroscience Shanghai Institutes for Biological Sciences Chinese Academy of Sciences 320 Yue Yang Road Shanghai 200031 China Correspondence Jiu lin Du

    Original URL path: http://www.cell-research.com/arts.asp?id=1787 (2016-02-14)
    Open archived version from archive

  • Cell Research
    Mao 1 Ailing Lu 1 Hongbin Wang 1 Wei Chen 1 Bin Xu 4 Qibin Leng 1 Cunshuan Xu 3 Guiwen Yang 2 Liguo An 2 Li Ping Zhu 4 and Guangxun Meng 1 1 Key Laboratory of Molecular Virology and Immunology Institut Pasteur of Shanghai Shanghai Institutes for Biological Sciences Graduate University of Chinese Academy of Sciences Shanghai 200025 China 2 College of Life Science Shandong Normal University Jinan

    Original URL path: http://www.cell-research.com/arts.asp?id=1788 (2016-02-14)
    Open archived version from archive

  • Cell Research
    Yiming Wu 1 Huirong Li 2 Xi Jin 2 Ling Hou 2 Kejing Deng 1 Tian Xu 1 3 and Wufan Tao 1 1 State Key Laboratory of Genetic Engineering and Institute of Developmental Biology and Molecular Medicine School of Life Science Fudan University Shanghai 200433 China 2 Developmental Cell Biology and Disease Program State Key Laboratory Cultivation Base and Key Laboratory of Vision Science of Ministry of Health Wenzhou

    Original URL path: http://www.cell-research.com/arts.asp?id=1792 (2016-02-14)
    Open archived version from archive

  • Cell Research

    (No additional info available in detailed archive for this subpage)
    Original URL path: /artsmore1.asp?id=158 (2016-02-14)


  • Cell Research
    1 MRC Human Genetics Unit Institute of Genetics and Molecular Medicine University of Edinburgh Crewe Road Edinburgh EH4 2XU UK 2 Centre for Cardiovascular Science Queen s Medical Research Institute University of Edinburgh 47 Little France Crescent Edinburgh EH16 4TJ UK Correspondence Richard R Meehan E mail Richard Meehan igmm ed ac uk CG rich DNA reader proteins that bind non methylated CpG sequences have emerged as critical factors to

    Original URL path: http://www.cell-research.com/arts.asp?id=1793 (2016-02-14)
    Open archived version from archive



  •