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  • Cell Research
    10 NF YB1 regulated expression of sucrose transporters in aleurone facilitates sugar loading to rice endosperm OPEN Ai Ning Bai 1 2 Xiao Duo Lu 1 Dong Qi Li 1 2 Jin Xin Liu 1 and Chun Ming Liu 1 1 Key Laboratory of Plant Molecular Physiology Institute of Botany Chinese Academy of Sciences Nanxincun 20 Fragrant Hill Beijing 100093 China 2 University of Chinese Academy of Sciences 19A Yuquan Road Beijing 100049 China Correspondence Chun Ming Liu Tel 86 010 6283 6663 E mail cmliu ibcas ac cn Cereal endosperms which consist of an outer aleurone layer and an inner starchy endosperm provide over 70 staple food for human www fao org Rice endosperm development occurs in the caryopsis of a grain During the grain filling stage sucrose produced in photosynthetic leaves is transported to grains via the phloem1 2 It has been proposed that sucrose upon arrival in the caryopsis through the phloem located at the dorsal vascular bundle is partially hydrolyzed by cell wall invertases CINs into glucose and fructose3 4 Since endosperm is symplastically isolated from maternal tissues it is assumed that these sugars are delivered to the endosperm actively through an apoplastic pathway by sugar

    Original URL path: http://www.cell-research.com/aoparts.asp?id=419 (2016-02-14)
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  • Cell Research
    10 Pathway mining based integration of critical enzyme parts for de novo biosynthesis of steviolglycosides sweetener in Escherichia coli Jianfeng Wang Shiyuan Li Zhiqiang Xiong and Yong Wang The development of microbial synthetic biology has been revolutionizing the industrial production of important plant terpenoids since the dawn of the century1 2 By reconstructing the downstream biosynthetic pathways and systematically engineering the supply of common terpenoid precursors the engineered microorganism chassis

    Original URL path: http://www.cell-research.com/aoparts.asp?id=413 (2016-02-14)
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  • Cell Research
    Preethi Padmanaban 1 2 Shaokui Ge 2 April Smith 3 Russell Fletcher 4 Ariane Baudhuin Kessel 4 Terry P Yamaguchi 5 Richard A Lang 3 and Lu Chen 1 2 1 Vision Science Graduate Group University of California Berkeley CA USA 2 Center for Eye Disease and Development Program in Vision Science and School of Optometry University of California Berkeley CA USA 3 Visual Systems Group Cincinnati Children s Hospital Medical Center Cincinnati OH USA 4 Department of Molecular and Cell Biology University of California Berkeley CA USA 5 Center for Cancer Research National Institutes of Health Frederick MD USA Correspondence Lu Chen Tel 1 510 642 5076 E mail chenlu berkeley edu Lymphatic research signifies a field of explosive discovery in recent years1 2 3 The lymphatic network penetrates most tissues in the body and its dysfunction has been found in a broad spectrum of disorders from inflammation to cancer metastasis and transplant rejection However to date there are few effective treatments for lymphatic diseases It is therefore important and urgent to investigate the fundamental mechanisms of pathological lymphangiogenesis LG the formation of new lymphatic vessels for the development of new therapeutic strategies The cornea offers an ideal site

    Original URL path: http://www.cell-research.com/aoparts.asp?id=407 (2016-02-14)
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  • Cell Research
    diversity of cell populations in a stem cell culture FREE Inha Heo 1 and Hans Clevers 1 1 Hubrecht Institute Royal Academy of Arts and Science KNAW and University Medical Centre Utrecht Uppsalalaan 8 3584CT Utrecht The Netherlands Correspondence Hans Clevers E mail h clevers hubrecht eu Culturing intestinal stem cells into 3D organoids results in heterogeneous cell populations reflecting the in vivo cell type diversity In a recent paper

    Original URL path: http://www.cell-research.com/aoparts.asp?id=386 (2016-02-14)
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  • Cell Research
    factor 10 526 Thomson Reuters 2013 Free Sample Issue Submission Advanced Online Publication Current Issue Top 10 Targeted genome editing in primate embryos FREE Xiangyu Guo 1 and Xiao Jiang Li 1 2 1 Institute of Genetics and Developmental Biology Chinese Academy of Sciences Beijing 100101 China 2 Department of Human Genetics Emory University School of Medicine Atlanta GA 30322 USA Correspondence Xiao Jiang Li E mail xli2 emory edu

    Original URL path: http://www.cell-research.com/aoparts.asp?id=366 (2016-02-14)
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  • Cell Research
    immunity join forces to promote metastatic spread FREE Zvi G Fridlender 1 Steven M Albelda 2 and Zvi Granot 3 1 Institute of Pulmonary Medicine Hadassah Hebrew University Medical Center 91120 Jerusalem Israel 2 Thoracic Oncology Research Laboratory University of Pennsylvania Philadelphia PA 19104 USA 3 Department of Developmental Biology and Cancer Research Institute for Medical Research Israel Canada Hebrew University Medical School 91120 Jerusalem Israel Correspondence Zvi Granot Steven

    Original URL path: http://www.cell-research.com/aoparts.asp?id=364 (2016-02-14)
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  • Cell Research
    Li Reginald Valdez Joseph Loureiro Xiaodong Cheng En Li Bernd Kinzel Mark Labow and Taiping Chen The authors unanimously wish to retract this paper because the calcium calmodulin dependent protein kinase 2 CamKII was erroneously equated with CK2 Casein Kinase 2 throughout the paper While all the results were valid and supported the major conclusions the confusion between CamKII and CK2 led to misinterpretation of some data Specifically the speculation

    Original URL path: http://www.cell-research.com/aoparts.asp?id=49 (2016-02-14)
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  • Cell Research
    02139 USA 2 Epigenetics Program Novartis Institutes for BioMedical Research Cambridge MA 02139 USA 3 Department of Biochemistry Emory University Atlanta GA 30322 USA 4 Developmental and Molecular Pathways Novartis Institutes for BioMedical Research Novartis Pharma AG Forum 1 Novartis Campus CH 4056 Basel Switzerland 5 Current address Department of Molecular Carcinogenesis The University of Texas MD Anderson Cancer Center Smithville TX 78957 USA Correspondence Taiping Chen Tel 1 512 237 9479 Fax 1 512 237 2475 E mail tchen2 mdanderson org Lysine specific demethylase 1 LSD1 AOF2 KDM1A the first enzyme with specific lysine demethylase activity to be described demethylates histone and non histone proteins and is essential for mouse embryogenesis LSD1 interacts with numerous proteins through several different domains most notably the tower domain an extended helical structure that protrudes from the core of the protein While there is evidence that LSD1 interacting proteins regulate the activity and specificity of LSD1 the significance and roles of such interactions in developmental processes remain largely unknown Here we describe a hypomorphic LSD1 allele that contains two point mutations in the tower domain resulting in a protein with reduced interaction with known binding partners and decreased enzymatic activity Mice homozygous for

    Original URL path: http://www.cell-research.com/aoparts.asp?id=50 (2016-02-14)
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