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  • Cell Research

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    Original URL path: /artsmore1.asp?id=146 (2016-02-14)



  • Cell Research
    2012 impact factor 10 526 Thomson Reuters 2013 Free Sample Issue Submission Advanced Online Publication Current Issue Top 10 VOLUME 23 ISSUE 2 2 2013 167 167 Xiaocheng Gu 1930 2012 Jun Ying Yuan 1 Xiao Hong Sun 2 and Ming Luo 3 E mail Junying yuan hms harvard edu sunx omrf org mingluo uab edu Cell Research 2013 23 167 doi 10 1038 cr 2013 18 published online 4

    Original URL path: http://www.cell-research.com/arts.asp?id=1601 (2016-02-14)
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  • Cell Research
    Immunology 364 Plantation Street LRB 370M Worcester MA 01605 USA 3 Deutsches Zentrum für Neurodegenerative Erkrankungen DZNE Sigmund Freud Str 25 Bonn 53127 Germany Correspondence Eicke Latz E mail eicke latz uni bonn de Inflammasomes are multiprotein complexes that detect and respond to foreign and endogenous danger signals by activating caspase 1 active caspase 1 in turn matures the pro inflammatory IL 1β family cytokines by cleaving their pro forms

    Original URL path: http://www.cell-research.com/arts.asp?id=1602 (2016-02-14)
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  • Cell Research
    them Ehsan Pourkarimi 1 and Anton Gartner 1 1 Wellcome Trust Centre for Gene Regulation and Expression University of Dundee Dundee DD1 5EH UK Correspondence Anton Gartner E mail a gartner dundee ac uk Seminal studies in C elegans contributed to our general understanding of programmed cell death conferred by apoptosis A recent study unravelled a new form of cell death in the worm and provided insights into its regulation

    Original URL path: http://www.cell-research.com/arts.asp?id=1603 (2016-02-14)
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  • Cell Research
    2Department of Pathology University of California San Diego La Jolla CA 92093 USA 3Division of Biological Sciences University of California San Diego La Jolla CA 92093 USA Correspondence Dong Er Zhang E mail d7zhang ucsd edu Interferon gamma IFN γ is crucial for immunity against different pathogens due to its broad effects on the multiple arms of the immune system The regulation of IFN γ immunity is of extensive interest

    Original URL path: http://www.cell-research.com/arts.asp?id=1604 (2016-02-14)
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  • Cell Research
    North Torrey Pines Road La Jolla CA 92037 USA 2Center for Regenerative Medicine in Barcelona Dr Aiguader 88 08003 Barcelona Spain Correspondence Juan Carlos Izpisua Belmonte Tel 1 858 453 4100 E mail belmonte salk edu izupisua cmrb eu Blood transfusion medicine requires a constant supply of platelets which is now totally donor dependent Recent advances in the generation of platelets in vitro through megakaryocytes MKs may provide protocols not

    Original URL path: http://www.cell-research.com/arts.asp?id=1605 (2016-02-14)
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  • Cell Research
    Center New York NY 10065 USA 2Louis V Gerstner Jr Graduate School of Biomedical Sciences Memorial Sloan Kettering Cancer Center New York NY 10065 USA Correspondence Johanna A Joyce E mail joycej mskcc org Resistance to molecularly targeted therapies can result from genomic alterations in the tumor cells that reactivate oncogenic signaling Less is known of tumor cell extrinsic mechanisms of resistance to targeted therapies Two recent studies have identified

    Original URL path: http://www.cell-research.com/arts.asp?id=1606 (2016-02-14)
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  • Cell Research
    or two signals Nicholas Chiorazzi 1 and Dimitar G Efremov 2 1Karches Center for Chronic Lymphocytic Leukemia Research The Feinstein Institute for Medical Research Hofstra North Shore LIJ School of Medicine 350 Community Drive Manhasset NY 10030 USA 2Molecular Hematology International Centre for Genetic Engineering and Biotechnology CNR Campus A Buzzati Traverso Rome Italy Correspondence Nicholas Chiorazzi Dimitar G Efremov E mail nchizzi NSHS edu efremov icgeb org The significant correlation between disease aggressiveness and the gene and protein structures of the B cell receptors BCRs expressed on chronic lymphocytic leukemia CLL cells together with the evidence for chronic activation of the BCR pathway have led to the hypothesis that this leukemia initiates and progresses by selecting normal B lymphocytes reactive with a restricted set of auto antigens A study recently published in Nature identified a novel signal initiating interaction between the third complementary determining region of the IG heavy chain variable domain HCDR3 and an epitope in the second framework region FR2 that appears to be unique to CLL B cells and that calls into question the need for classical antigen binding in the activation and expansion of the leukemic cells These findings are discussed in the context of

    Original URL path: http://www.cell-research.com/arts.asp?id=1607 (2016-02-14)
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