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  • Cell Research
    5 2015 638 641 Regulation of transcriptionally active genes via the catalytically inactive Cas9 in C elegans and D rerio Lijiang Long 1 Hong Guo 1 Di Yao 1 Kai Xiong 1 Yongjun Li 1 Pengpeng Liu 1 Zuoyan Zhu 1 and Dong Liu 1 1 The Education Ministry Key Laboratory of Cell Proliferation and Differentiation and the State Key Laboratory of Bio membrane and Membrane Bio engineering School of

    Original URL path: http://www.cell-research.com/arts.asp?id=2106 (2016-02-14)
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  • Cell Research
    Reuters 2013 Free Sample Issue Submission Advanced Online Publication Current Issue Top 10 VOLUME 25 ISSUE 5 5 2015 642 644 Paternally contributed centrioles exhibit exceptional persistence in C elegans embryos OPEN Fernando R Balestra 1 Lukas von Tobel 1 and Pierre Gönczy 1 1 Swiss Institute for Experimental Cancer Research ISREC School of Life Sciences Swiss Federal Institute of Technology EPFL Lausanne Switzerland Correspondence Pierre Gönczy E mail pierre

    Original URL path: http://www.cell-research.com/arts.asp?id=2107 (2016-02-14)
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  • Cell Research
    progenitor cells by chemical cocktails and hypoxia FREE Lin Cheng 1 Wenxiang Hu 1 Binlong Qiu 1 Jian Zhao 1 Yongchun Yu 2 Wuqiang Guan 2 Min Wang 2 Wuzhou Yang 2 and Gang Pei 1 3 1 State Key Laboratory of Cell Biology Institute of Biochemistry and Cell Biology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences 320 Yueyang Road Shanghai 200031 China 2 Institute of Neurobiology Institutes

    Original URL path: http://www.cell-research.com/arts.asp?id=2108 (2016-02-14)
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  • Cell Research

    (No additional info available in detailed archive for this subpage)
    Original URL path: /artsmore1.asp?id=42 (2016-02-14)


  • Cell Research
    Submission Advanced Online Publication Current Issue Top 10 VOLUME 20 ISSUE 1 1 2010 1 3 Mobilizing forces CD4 helper T cells script adaptive immunity Frédérick Masson and Gabrielle T Belz Division of Immunology The Walter and Eliza Hall Institute of Medical Research 1G Royal Parade Melbourne Victoria 3052 Australia Correspondence Gabrielle T Belz Tel 61 3 9345 2544 E mail belz wehi edu au Cell Research 2010 20 1

    Original URL path: http://www.cell-research.com/arts.asp?id=584 (2016-02-14)
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  • Cell Research
    Bethesda MD 20892 USA Correspondence Jinfang Zhu William E Paul E mail jfzhu niaid nih gov wpaul niaid nih gov CD4 T helper Th cells play critical roles in adaptive immune responses They recruit and activate other immune cells including B cells CD8 T cells macrophages mast cells neutrophils eosinophils and basophils Based on their functions their pattern of cytokine secretion and their expression of specific transcription factors Th cells differentiated from na飗e CD4 T cells are classified into four major lineages Th1 Th2 Th17 and T regulatory Treg cells although other Th lineages may exist Subsets of the same lineage may express different effector cytokines reside at different locations or give rise to cells with different fates whereas cells from different lineages may secrete common cytokines such as IL 2 IL 9 and IL 10 resulting in massive heterogeneity of the Th cell population In addition the pattern of cytokine secretion may switch from that of one lineage toward another under certain circumstances suggesting that Th cells are plastic Tregs are also more heterogeneous and plastic than were originally thought In this review we summarize recent reports on heterogeneity and plasticity of Th cells and discuss potential mechanisms and

    Original URL path: http://www.cell-research.com/arts.asp?id=585 (2016-02-14)
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  • Cell Research
    of memory CD8 T cells Joanna R DiSpirito 1 and Hao Shen 1 2 1 Department of Microbiology University of Pennsylvania School of Medicine Philadelphia PA 19104 USA 2 Shanghai Institute of Immunology Shanghai JiaoTong University School of Medicine Shanghai 200025 China Correspondence Hao Shen Tel 215 573 5259 E mail hshen mail med upenn edu The complement system plays a crucial role in the innate defense against common pathogens Activation of complement leads to robust and efficient proteolytic cascades which terminate in opsonization and lysis of the pathogen as well as in the generation of the classical inflammatory response through the production of potent proinflammatory molecules More recently however the role of complement in the immune response has been expanded due to observations that link complement activation to adaptive immune responses It is now appreciated that complement is a functional bridge between innate and adaptive immune responses that allows an integrated host defense to pathogenic challenges As such a study of its functions allows insight into the molecular underpinnings of host pathogen interactions as well as the organization and orchestration of the host immune response This review attempts to summarize the roles that complement plays in both innate and

    Original URL path: http://www.cell-research.com/arts.asp?id=586 (2016-02-14)
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  • Cell Research
    Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda MD 20892 USA Correspondence Fengyi Wan Tel 1 301 402 2419 E mail fwan niaid nih gov The nuclear factor kappa B NF κB transcription factor plays a critical role in diverse cellular processes associated with proliferation cell death development as well as innate and adaptive immune responses NF κB is normally sequestered in the cytoplasm by a family of inhibitory proteins known as inhibitors of NF κB IκBs The signal pathways leading to the liberation and nuclear accumulation of NF κB which can be activated by a wide variety of stimuli have been extensively studied in the past two decades After gaining access to the nucleus NF κB must be actively regulated to execute its fundamental function as a transcription factor Recent studies have highlighted the importance of nuclear signaling in the regulation of NF κB transcriptional activity A non Rel subunit of NF κB ribosomal protein S3 RPS3 and numerous other nuclear regulators of NF κB including Akirin Nurr1 SIRT6 and others have recently been identified unveiling novel and exciting layers of regulatory specificity for NF κB in the nucleus Further insights into the nuclear events that

    Original URL path: http://www.cell-research.com/arts.asp?id=587 (2016-02-14)
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