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  • Cell Research
    Insect Developmental and Evolutionary Biology Institute of Plant Physiology and Ecology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai 200032 China 2 Department of Molecular Biology and Genetics Howard Hughes Medical Institute Johns Hopkins University School of Medicine Baltimore MD 21205 USA Correspondence Sheng Li Tel 86 21 54924163 E mail shengli sippe ac cn Animal cells require extrinsic cues for growth proliferation and survival The propagation of Drosophila imaginal disc cells in vitro for example requires the supplementation of fly extract the composition of which remains largely undefined Here I report the biochemical purification of iron loaded ferritin as an active ingredient of fly extract that is required for promoting the growth of clone 8 imaginal disc cells Consistent with an essential role for iron loaded ferritin in cultured cells overexpression of ferritin or addition of iron in a nutrient poor diet increases animal viability and body weight promotes cell proliferation and shortens the duration of postembryonic development Conversely overexpression of dominant negative ferritin or addition of iron chelator causes the opposite effects Ferritin mutant flies arrest development at the first instar larval stage with a severe starvation phenotype reminiscent of that seen in starved larvae I

    Original URL path: http://www.cell-research.com/arts.asp?id=466 (2016-02-14)
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  • Cell Research
    VOLUME 20 ISSUE 10 10 2010 1158 1169 miR 223 and miR 142 attenuate hematopoietic cell proliferation and miR 223 positively regulates miR 142 through LMO2 isoforms and CEBP β Wei Sun Wenwen Shen Shuang Yang Fen Hu Huihui Li and Tian Hui Zhu Laboratory of Molecular Genetics College of Medicine Nankai University Tianjin 300071 China Correspondence Tian Hui Zhu Tel 86 22 23505501 E mail zhuth nankai edu cn miR 142 and miR 223 have been identified as hematopoietic specific microRNAs miR 223 has crucial functions in myeloid lineage development However the function of miR 142 remains unclear In this study we found that both miR 142 and miR 223 attenuated the proliferation of hematopoietic cells and that miR 223 up regulated miR 142 expression through the LMO2 L S isoforms and CEBP β miR 223 negatively regulated both LMO2 L S isoforms and CEBP β post transcriptionally while CEBP β positively regulated the LMO2 L S isoforms and both of the LMO2 L S isoforms negatively regulated miR 142 These results reveal a novel miR 223 CEBP β LMO2 miR 142 regulatory pathway which has pivotal functions in hematopoiesis Cell Research 2010 20 1158 1169 doi 10 1038

    Original URL path: http://www.cell-research.com/arts.asp?id=467 (2016-02-14)
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  • Cell Research
    to tumor protein enhance the uptake of tumor antigens by human dendritic cells in vitro Zhao Sun 1 Wei Wang 2 Jie Meng 2 Shuchang Chen 1 Haiyan Xu 2 and Xian Da Yang 2 1 Department of Oncology Peking Union Medical College Hospital Beijing 100730 China 2 Institute of Basic Medical Sciences Peking Union Medical College Chinese Academy of Medical Sciences Beijing 100730 China Correspondence Xian Da Yang Haiyan

    Original URL path: http://www.cell-research.com/arts.asp?id=468 (2016-02-14)
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  • Cell Research

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    Original URL path: /artsmore1.asp?id=32 (2016-02-14)


  • Cell Research
    Online Publication Current Issue Top 10 VOLUME 20 ISSUE 11 11 2010 1175 1177 Not miR ly aging SIRT1 boosts memory via a microRNA dependent mechanism Silvia Bicker and Gerhard Schratt Interdisziplinäres Zentrum f黵 Neurowissenschaften SFB488 Junior Group Universität Heidelberg and Institut f黵 Neuroanatomie Universitätsklinikum Heidelberg Im Neuenheimer Feld 345 D 69120 Heidelberg Germany Correspondence Gerhard Schratt Tel 49 6221 566210 E mail schratt ana uni heidelberg de Cell Research

    Original URL path: http://www.cell-research.com/arts.asp?id=445 (2016-02-14)
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  • Cell Research
    Top 10 VOLUME 20 ISSUE 11 11 2010 1178 1180 IκBβ is a positive and negative regulator of NF κB activity during inflammation Hideaki Kamata Yoshihiro Tsuchiya and Tomoichiro Asano Laboratory of Biomedical Chemistry Department of Molecular Medical Science Graduate School of Biomedical Science Hiroshima University Kasumi 1 2 3 Minami ku Hiroshima 734 8553 Japan Correspondence Hideaki Kamata Tel 81 82 257 5138 E mail hkamata hiroshima u ac

    Original URL path: http://www.cell-research.com/arts.asp?id=446 (2016-02-14)
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  • Cell Research
    Issue Submission Advanced Online Publication Current Issue Top 10 VOLUME 20 ISSUE 11 11 2010 1181 1184 Autophagosome formation not necessarily an inside job Andrea Longatti Andrea Orsi1 and Sharon A Tooze London Research Institute Cancer Research UK 44 Lincoln s Inn Fields London WC2A 3PX United Kingdom Correspondence Sharon A Tooze Tel 44 207 269 3122 E mail Sharon tooze cancer org uk Cell Research 2010 20 1181 1184

    Original URL path: http://www.cell-research.com/arts.asp?id=447 (2016-02-14)
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  • Cell Research
    48109 USA 2 Department of Microbiology and Immunology University of Michigan Medical School Ann Arbor Michigan 48109 USA 3 Department of Epidemiology University of Michigan Ann Arbor Michigan 48109 USA Correspondence Kathleen L Collins Tel 734 615 1320 E mail klcollin umich edu Currently available anti HIV 1 drugs suppress viral replication and maintain viral levels below the detection threshold of most assays but do not eliminate cellular reservoirs As

    Original URL path: http://www.cell-research.com/arts.asp?id=448 (2016-02-14)
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