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  • Cell Research
    21 ISSUE 9 9 2011 1370 1373 Essential role of DOT1L in maintaining normal adult hematopoiesis Anh T Nguyen 1 2 Jin He 1 2 Olena Taranova 1 2 and Yi Zhang 1 2 1 Howard Hughes Medical Institute 2 Department of Biochemistry and Biophysics Lineberger Comprehensive Cancer Center University of North Carolina at Chapel Hill Chapel Hill NC27599 7295 USA Correspondence Yi Zhang Tel 919 843 8225 E mail

    Original URL path: http://www.cell-research.com/arts.asp?id=306 (2016-02-14)
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  • Cell Research
    and insights into recognition of unmodified histone H3 arginine residue 2 Lulu Hu 1 2 Ze Li 2 Ping Wang 2 Yan Lin 2 and Yanhui Xu 1 2 3 1 Cancer Institute Shanghai Cancer Center Fudan University Department of Oncology Shanghai Medical College Fudan University Shanghai 200032 China 2 Institute of Biomedical Sciences Fudan University 138 Yixue Yuan Road Shanghai 200032 China 3 State Key Laboratory of Genetic Engineering

    Original URL path: http://www.cell-research.com/arts.asp?id=307 (2016-02-14)
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  • Cell Research
    of histone H3 tail by UHRF1 PHD finger Chengkun Wang 1 Jie Shen 1 Zhongzheng Yang 1 Ping Chen 2 Bin Zhao 1 Wei Hu 1 Wenxian Lan 1 Xiaotian Tong 1 Houming Wu 1 Guohong Li 2 an 1 State Key Laboratory of Bio organic and Natural Product Chemistry Shanghai Institute of Organic Chemistry Chinese Academy of Sciences Shanghai 200032 China 2 National Laboratory of Biomacromolecules Institute of Biophysics

    Original URL path: http://www.cell-research.com/arts.asp?id=308 (2016-02-14)
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  • Cell Research

    (No additional info available in detailed archive for this subpage)
    Original URL path: /artsmore1.asp?id=21 (2016-02-14)


  • Cell Research
    Issue Submission Advanced Online Publication Current Issue Top 10 VOLUME 21 ISSUE 10 10 2011 1386 1387 Turning skin into dopamine neurons Malin Parmar and Johan Jakobsson Department of Experimental Medical Science Wallenberg Neuroscience Center and Lund Stem Cell Center Lund University SE 221 84 Lund Sweden Correspondence Malin Parmar Johan Jakobsson E mail malin parmar med lu se malin parmar med lu se Cell Research 2011 21 1386 1387

    Original URL path: http://www.cell-research.com/arts.asp?id=283 (2016-02-14)
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  • Cell Research
    Huck Hui Ng 1 2 3 4 5 1 Department of Biochemistry Yong Loo Lin School of Medicine National University of Singapore 8 Medical Drive Singapore 117597 2 Gene Regulation Laboratory Genome Institute of Singapore 60 Biopolis Street Singapore 138672 3 NUS Graduate School for Integrative Sciences and Engineering National University of Singapore Singapore 117456 4 Department of Biological Sciences National University of Singapore Singapore 117597 5 School of Biological

    Original URL path: http://www.cell-research.com/arts.asp?id=284 (2016-02-14)
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  • Cell Research
    factor 10 526 Thomson Reuters 2013 Free Sample Issue Submission Advanced Online Publication Current Issue Top 10 VOLUME 21 ISSUE 10 10 2011 1391 1392 New blood brothers the GPR55 and CB 2 partnership Andy Irving Division of Medical Sciences University of Dundee UK DD1 9SY Correspondence Andy Irving E mail a j irving dundee ac uk Cell Research 2011 21 1391 1392 doi 10 1038 cr 2011 77 published

    Original URL path: http://www.cell-research.com/arts.asp?id=285 (2016-02-14)
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  • Cell Research
    1 Que Minh Ngo 1 Sarit Klugman 1 Keith A Ching 1 Lee E Edsall 1 1 Department of Cellular and Molecular Medicine Ludwig Institute for Cancer Research University of California San Diego School of Medicine La Jolla CA 92093 0653 USA 2 Morgridge Institute for Research Madison WI 53707 USA 3 Genome Center of Wisconsin University of Wisconsin Madison WI 53706 USA 4 Roche NimbleGen Madison WI 53719 USA 5 National Institutes of Allergy and Infectious Disease Rockville MD 20852 USA Correspondence James A Thomson Bing Ren E mail thomson primate wisc edu biren ucsd edu Pluripotency the ability of a cell to differentiate and give rise to all embryonic lineages defines a small number of mammalian cell types such as embryonic stem ES cells While it has been generally held that pluripotency is the product of a transcriptional regulatory network that activates and maintains the expression of key stem cell genes accumulating evidence is pointing to a critical role for epigenetic processes in establishing and safeguarding the pluripotency of ES cells as well as maintaining the identity of differentiated cell types In order to better understand the role of epigenetic mechanisms in pluripotency we have examined the dynamics of chromatin modifications genome wide in human ES cells hESCs undergoing differentiation into a mesendodermal lineage We found that chromatin modifications at promoters remain largely invariant during differentiation except at a small number of promoters where a dynamic switch between acetylation and methylation at H3K27 marks the transition between activation and silencing of gene expression suggesting a hierarchy in cell fate commitment over most differentially expressed genes We also mapped over 50 000 potential enhancers and observed much greater dynamics in chromatin modifications especially H3K4me1 and H3K27ac which correlate with expression of their potential target genes Further analysis of these

    Original URL path: http://www.cell-research.com/arts.asp?id=286 (2016-02-14)
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