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  • Cybergenetics :: Commonwealth of Pennsylvania v Jesse Lumberger
    County crime lab developed DNA mixture data from this biological evidence There was DNA from at least three people on each of the clothing items Match The crime lab s manual inclusion analysis of the DNA mixtures could not produce a match statistic much beyond a hundred thousand TrueAllele On the same DNA data the computer separated the mixtures into their genetic components TrueAllele connected Mr Lumberger to the blue

    Original URL path: http://www.cybgen.com/news/cases/Pennsylvania-v-Jesse-Lumberger.shtml (2016-02-12)
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  • Cybergenetics :: People of California v Billy Ray Johnson
    serial rapist gets life plus 432 years Crime In the summer of 2013 three women were sexually assaulted by a masked assailant in the East Side of Bakersfield CA Evidence Biological evidence was collected from three crime scenes These items included a phone clothing a bathtub handle and zip tie believed to have been used to bind a victim DNA The Kern Regional Crime Laboratory KRCL developed DNA data from 37 evidence items Match Due to the complexity of these low level 3 and 4 person mixtures human review of the data was largely inconclusive TrueAllele The computer yielded match statistics from 33 mixture items 8 of these items linked Johnson to the 3 crimes Cybergenetics and the KRCL independently obtained concordant TrueAllele match statistics Cybergenetics Dr Mark Perlin testified about the computer s DNA match statistics giving evidence at a grand jury hearing in December 2013 and again at Johnson s trial in March 2015 Outcome Mr Johnson was found guilty on 24 charges and was sentenced to life without parole plus 432 years to life Media Rapes have east Bakersfield residents on edge Newspaper Suspect announced Alleged serial rapist faces 21 charges Television New DNA analysis helps gain

    Original URL path: http://www.cybgen.com/news/cases/California-v-Billy-Ray-Johnson.shtml (2016-02-12)
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  • Cybergenetics :: State of Maryland v Nelson Clifford
    lab s manual mixture analysis gave inclusion statistics in the thousands between the two evidence items and Nelson Clifford Defendant The nature of the crimes Clifford has been accused of and the sheer number of times he has been accused of committing them is staggering said State s Attorney Marilyn Mosby Clifford was first convicted at age 18 in 1997 of sexually assaulting a woman at knife point After Clifford s release from prison in 2007 he allegedly committed nearly a half dozen sexual offenses 4 of which he was found not guilty At each trial despite DNA evidence linking him to his victims he was acquitted after taking the stand and claiming the sexual contact between him and his victims was consensual TrueAllele The computer separated the DNA mixtures into their three genetic components Comparing these evidence components with reference samples TrueAllele found the victim and boyfriend s DNA on the clothing The computer also tied the evidence to Clifford with a match statistic of 115 thousand to the brown belt and a statistic of 182 thousand to the green shirt Cybergenetics On May 7 2015 Cybergenetics chief scientist Dr Mark Perlin testified in the Baltimore trial about the

    Original URL path: http://www.cybgen.com/news/cases/Maryland-v-Nelson-Clifford.shtml (2016-02-12)
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  • Cybergenetics :: DNA Identification for Scientists: Basics
    must be tempered by the possibility of a coincidental match This lecture introduces the likelihood ratio LR that balances DNA identification with coincidence Download Transcript Download Handout Download PowerPoint Bayesian Belief Update When there is uncertainty our beliefs are expressed as probabilities In science we turn to data as a way of increasing our certainty in some hypotheses over others Bayes theorem is the mathematical way we update our beliefs

    Original URL path: http://www.cybgen.com/information/courses/2010/TAVC/Perlin_DNA_Identification_for_Scientists_Basics/page.shtml (2016-02-12)
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  • Cybergenetics :: DNA Identification for Scientists: Methods
    lecture shows how quantitative modeling exploits data variation to preserve DNA identification information while qualitative thresholds introduce error and discard information Download Handout Download PowerPoint Quantitative Data Modeling A quantitative data model includes many explanatory variables including genotypes mixture weight and data variance These variables and their uncertainty are determined by a joint probability distribution over all the data and parameters This lecture shows how using a quantitative likelihood function

    Original URL path: http://www.cybgen.com/information/courses/2010/TAVC/Perlin_DNA_Identification_for_Scientists_Methods/page.shtml (2016-02-12)
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  • Cybergenetics :: DNA Identification for Scientists: Special Topics
    one verdict 15 minutes Duquesne University 2010 Summer Research Symposium Keynote Address Pittsburgh PA July 2010 M W Perlin DNA identification science The search for truth 60 minutes Twentieth International Symposium on the Forensic Sciences of the Australian and New Zealand Forensic Science Society September 2010 M W Perlin and M Greenhalgh Scientific combination of DNA evidence A handgun mixture in eight parts 20 minutes M W Perlin and B

    Original URL path: http://www.cybgen.com/information/courses/2010/TAVC/Perlin_DNA_Identification_for_Scientists_Special_Topics/page.shtml (2016-02-12)
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  • Cybergenetics :: DNA Identification for Lawyers: CLE
    introduces the basic principles of DNA in the context of a homicide trial where computer DNA interpretation was used for the first time Download Handout Download Powerpoint Mixture Interpretation DNA evidence is often uncertain the data does not clearly indicate a single genetic source The most common cause of this genotype uncertainty is a DNA mixture of two or more individuals Different mixture interpretation methods infer different genotypes with some

    Original URL path: http://www.cybgen.com/information/courses/2010/DUCLE/Perlin_DNA_Identification_for_Lawyers_CLE/page.shtml (2016-02-12)
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