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  • e-Health Impact Questionnaire (eHIQ) - Isis Innovation
    Health Impact Questionnaire eHIQ The eHIQ assesses the impact of using health related websites Background The internet can be a valuable resource for accessing health information and support The e HIQ has been designed and developed to be used as an instrument to assess the effects of websites containing health information The eHIQ is a self complete questionnaire which is designed to be administered electronically as well as via a more conventional paper pen route The eHIQ instrument The eHIQ questionnaire consists of two independently administered and scored parts eHIQ Part 1 and eHIQ Part 2 eHIQ Part 1 11 Items where items represent general attitudes towards using the internet to access health information eHIQ Part 2 26 items where items measure a person s ease with using online information particularly emphasising a person s openness to learning and gaining support from other peoples experiences Both parts of the questionnaire have a five point response category for all items ranging from Strongly disagree to Strongly agree The eHIQ is supported by a comprehensive 22 page user guide which includes details of the development administration and scoring of the e HIQ Scoring System Raw scores can be calculated using a simple scoring algorithm for all subscales Raw scores are transformed to a 0 100 metric where 0 lowest possible negative value and 100 highest possible positive value for each respective subscale Development The eHIQ was developed using a four stage process as outlined below Stage 1 Item generation Items were informed through a review of relevant literature and secondary qualitative analysis of 99 patient carer interviews representing a range of health conditions Five themes were found to be applicable to the impact of using health related websites 1 Information 2 Feeling supported 3 Relationships with others 4 Experiencing health services and 5 Affecting behaviours Questionnaire items were derived from this activity and shown for review to an expert panel consisting of clinicians and academics with interests in the field of e health Stage 2 Cognitive de brief interviews Cognitive debrief interviews n 21 were used to assess items for face and content validity Cognitive interviewing confirmed the instructions were easy to understand and the rubric clearly indicated how participants were supposed to answer items participants found all items retained relevant to the topic and acceptable to answer the response options were appropriate to the item stem and the response options adequately covered the potential range of agreement and the electronic format was appropriate for use among a range of participants with varying levels of computer proficiency Items were deleted n 29 and added n 9 leaving 62 items Stage 3 Item reduction and scale generation Following expert and patient refinement two independent item pools were confirmed as suitable to enter psychometric testing The first item pool contained 23 items asking respondents about their general attitudes towards health related websites whilst the second item pool contained 39 items asking the respondent about their attitudes towards a specific health related website All items

    Original URL path: http://isis-innovation.com/outcome-measures/e-health-impact-questionnaire-ehiq/ (2016-05-01)
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  • The Mild Cognitive Impairment Questionnaire (MCQ) - Isis Innovation
    Use Inspired Works Contact us Incubator News Incubator Services Stages of Development Our Ventures Meet the CEOs Find your CEO match Incubator Team Contact For University Members Consulting Services Support FAQs Register as a consultant Commercialising Your Technology IP patents and licences Starting a company FAQs Isis Startup Incubator Oxford University Hospital NHS Foundation Trust Translational Funding University Hot Desks For Medical Sciences Researchers Contact Us News Events Publications News Events Request further information Technology Showcase 2016 Success Stories Publications Annual Reports Innovation Insights Isis newsletters Comment opinion Other publications reports Home Health outcome measures Clinical Outcomes Assessments The Mild Cognitive Impairment Questionnaire MCQ Share this The Mild Cognitive Impairment Questionnaire MCQ The Mild Cognitive Impairment Questionnaire MCQ is a self report 13 item PRO developed to assess quality of life QoL in people with mild cognitive impairment MCI Background The MCQ is the first PRO measure to be developed specifically to assess QoL in people with MCI The MCQ taps into two domains of patient reported quality of life namely Emotional Effects 6 items and Practical Concerns 7 items The MCQ is available as a self report measure but can also be accompanied by an advocate carer s version separate 14 items of the measure The MCQ was created on the basis of patient report and has been shown to have good psychometric properties The development of the MCQ closely followed FDA guidance on the development of PRO measures for use in supporting label claims FDA December 2009 where possible The MCQ has been developed so it can be used to assess outcomes following intervention such as cognitive rehabilitation or potential pharmacological therapies for MCI It is a short simple assessment tool taking only about 5 minutes to complete for use in a variety of clinical and research settings to assess the effect of interventions for people with MCI The MCQ could theoretically be applied to mild dementia but this application has not been validated yet Scoring System The 13 item MCQ provides scores for each of the 2 domains Alternatively the sum of the scores can provide a single figure used to assess the overall health related quality of life profile of the individual questioned Details of the scoring system and administration procedures for MCQ and MCQ Carer are provided in the user guide that accompanies the MCQ MCQ Carer Development The MCQ was developed and tested in a comprehensive three stage process Stage 1 Item generation Semi structured in depth interviews were carried out with 23 people recently diagnosed with MCI A set of preliminary questionnaire items were then discussed with an expert panel and refined to produce a draft questionnaire The draft questionnaire was then discussed with a focus group of 11 people with MCI resulting in a final draft 17 itme questionnaire Stage 2 Item reduction and scale generation A first postal study n 280 resulting in 146 completed questionnaires was conducted using the 17 item questionnaire generated at stage one along with the SF

    Original URL path: http://isis-innovation.com/outcome-measures/mild-cognitive-impairment-questionnaire-mcq/ (2016-05-01)
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  • The Oxford Cognitive Screen (OCS) - Isis Innovation
    Researchers Contact Us News Events Publications News Events Request further information Technology Showcase 2016 Success Stories Publications Annual Reports Innovation Insights Isis newsletters Comment opinion Other publications reports About Groups People Overview Board Overview Networks Oxford Innovation Society Isis Angels Network Other Networks Isis Innovation in China Jobs Other Languages Contact us Technologies Available Explore Technologies for License Intellectual Property IP for SMEs Material Reagent Sales Easy to use Materials Evaluation Agreement Investment Opportunities Technology investment opportunities Information for Investors Isis Innovation spinouts Oxford Invention Fund University of Oxford Isis Funds Oxford University Consulting Services Academic consulting advice Academic Expertise Showcases Technical Services Technical Services Showcases OUC Clients For University members Contact OUC Innovation Consultancy Technology Transfer Commercialisation Training Technology Transfer Services Technology Commercialisation Innovation Management Case Study Overview Contact us Health Outcomes iOutcomes People Overview Clinical Outcomes Assessments Health Outcome Services FAQs Apply to Use Inspired Works Contact us Incubator News Incubator Services Stages of Development Our Ventures Meet the CEOs Find your CEO match Incubator Team Contact For University Members Consulting Services Support FAQs Register as a consultant Commercialising Your Technology IP patents and licences Starting a company FAQs Isis Startup Incubator Oxford University Hospital NHS Foundation Trust Translational Funding University Hot Desks For Medical Sciences Researchers Contact Us News Events Publications News Events Request further information Technology Showcase 2016 Success Stories Publications Annual Reports Innovation Insights Isis newsletters Comment opinion Other publications reports Home Health outcome measures Clinical Outcomes Assessments The Oxford Cognitive Screen OCS Share this The Oxford Cognitive Screen OCS Up to now no short efficient cognitive screening tool was available that targets stroke survivors The OCS Oxford Cognitive Screen can be delivered at the bedside in acute stroke is easy to administer and score and is inclusive for patients with aphasia and neglect It

    Original URL path: http://isis-innovation.com/outcome-measures/the-oxford-cognitive-screen-ocs/ (2016-05-01)
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  • The Oxford Shoulder Score (OSS) - Isis Innovation
    Services FAQs Apply to Use Inspired Works Contact us Incubator News Incubator Services Stages of Development Our Ventures Meet the CEOs Find your CEO match Incubator Team Contact For University Members Consulting Services Support FAQs Register as a consultant Commercialising Your Technology IP patents and licences Starting a company FAQs Isis Startup Incubator Oxford University Hospital NHS Foundation Trust Translational Funding University Hot Desks For Medical Sciences Researchers Contact Us News Events Publications News Events Request further information Technology Showcase 2016 Success Stories Publications Annual Reports Innovation Insights Isis newsletters Comment opinion Other publications reports Home Health outcome measures Clinical Outcomes Assessments The Oxford Shoulder Score OSS Share this The Oxford Shoulder Score OSS The Oxford Shoulder Score OSS is a 12 item patient reported PRO specifically designed and developed for assessing outcomes of shoulder surgery e g for assessing the impact on patients quality of life of degenerative conditions such as arthritis and rotator cuff problems Background The development of the OSS was driven by demands for a suitable PRO by orthopaedic surgeons who wished to measure the outcomes of their treatments from the patient s perspective The OSS was designed and developed by researchers within the Health Services Research unit part of the Nuffield Department of Population Health at the University of Oxford who also created the Oxford Hip and Knee scores which are used for assessment of all NHS hip and knee surgeries approximately 120 000 since April 2009 Designed and developed in association with surgical colleagues at the Nuffield Orthopaedic Centre the OSS has been tested in a surgical context with patients and shown to be reliable valid and responsive First published in 1996 the OSS has gradually been adopted as an outcome measure and is now widely used in clinical studies Properties of the Oxford Shoulder Score include the only condition specific PRO designed and developed for use in assessing surgery intervention of the shoulder has undergone rigorous testing for validity reliability and sensitivity to change and has been shown to be a robust tool for assessing the outcome of shoulder surgery can be employed in surveys or clinical trials for shoulder surgery patient groups has been shown to be highly responsive to interventions and can be used as an indicator for recovery and general improvement in quality of life following shoulder surgery brief and easy to complete resulting in good return rates the PRO can be completed anywhere and delivered by post electronically making follow up of large numbers of patients much more feasible and cheaper than conducting clinical assessments easy to interpret scores The PRO The Oxford Shoulder Score is a unidimensional score comprising 12 questions A single score is derived from the PRO Substantial evidence from clinical studies shows that the PRO has high internal consistency and is a valid and reliable measure of patient well being Example Studies The OSS is primarily used to assess outcomes of shoulder surgery including total shoulder replacement and reverse shoulder replacement Other uses of the

    Original URL path: http://isis-innovation.com/outcome-measures/oxford-shoulder-score-oss/ (2016-05-01)
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  • The Oxford Depression Questionnaire (ODQ) - Isis Innovation
    patents and licences Starting a company FAQs Isis Startup Incubator Oxford University Hospital NHS Foundation Trust Translational Funding University Hot Desks For Medical Sciences Researchers Contact Us News Events Publications News Events Request further information Technology Showcase 2016 Success Stories Publications Annual Reports Innovation Insights Isis newsletters Comment opinion Other publications reports Home Health outcome measures Clinical Outcomes Assessments The Oxford Depression Questionnaire ODQ Share this The Oxford Depression Questionnaire ODQ The Oxford Depression Questionnaire ODQ is a patient centred self report measure of emotional symptoms present in patients treated with antidepressants Background Some patients with major depression report a restricted range of emotions that may appear to arise as a side effect of treatment with antidepressants It is uncertain whether this phenomenon sometimes called emotional blunting represents residual symptoms of depression or side effects of antidepressant treatment The Oxford Depression Questionnaire ODQ is a patient centred self report measure of emotional symptoms present in patients treated with antidepressants The key characteristics and benefits of the ODQ based on results acquired during development are Acceptability Completion of the questionnaire by patients was extremely high with 96 completing the instrument on 3 separate occasions weeks 0 1 and 4 Validity The ODQ has high construct validity with four dimensions reduction in positive emotions general reduction in emotions not caring and emotional detachment being represented in the ODQ In addition items in the ODQ demonstrate close relationships to contents of other scores measuring emotional blunting Sensitivity to change When compared to a gold standard question relating to the participant s experience of emotional side effects the ODQ appears to be sensitive to change Reliability The ODQ has high reliability both in terms of internal reliability items within each construct were highly correlated and test retest reliability The PRO The ODQ is a 26 item patient self complete measure spread over 3 sections and covering 4 dimensions derived from qualitative research of not caring NC emotional detachment ED positive reduction PR general reduction GR The 3 sections of the ODQ are Section 1 12 items three items from each of the 4 dimensions NC ED PR and GR Recall period is the last week Section 2 8 items 2 from each of the four dimensions comparing respondents experiences during the previous week with in comparison to their experiences before they developed their illness problem Section 3 6 items is for completion by those respondents currently prescribed antidepressants This section addresses the extent to which participants attribute their emotional difficulties to their antidepressant and the extent to which they would therefore be considered by participants to be emotional side effects It also addresses the possible impact of emotional side effects on antidepressant adherence Response options are based on 5 point likert scale with a score applied to each response Results can be presented on a dimension basis or summed to give an overall ODQ score If required an additional dimension Antidepressant as cause AC can also be scored Full details of scoring and handling

    Original URL path: http://isis-innovation.com/outcome-measures/the-oxford-depression-questionnaire-odq/ (2016-05-01)
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  • The Oxford Ankle Foot Questionnaire for Children (OxAFQ-C) - Isis Innovation
    child and parent caregivers perspective The OxAFQ C has broad utility both in routine clinical settings or applied research comparing different treatment programmes used in paediatric orthopaedics trauma and rheumatology A short 15 item questionnaire that has proven to be easy to complete and returns high completion rates Has been proven to be a valid and reliable Morris et al 2008 see reference below as well as being responsive and longitudinally valid Morris et al 2009 see reference below The PRO The OxAFQ C has 15 items 14 of which are used to calculate domain scores Physical 6 items School and Play 4 items Emotional 4 items A final item item 15 Has your foot or ankle stopped you wearing any shoes you wanted to wear was added to reflect the concern by many children that they can or cannot wear the footwear they prefer Example Studies These are some of the more specific ways the OxAFQ C is currently employed by our user community Clinical investigation into the impact of foot anomalies for patients with Aperts Syndrome A pilot study foot pain and shape in teenagers Multi Centre randomised controlled trial Heel raises versus prefabricated orthoses in the treatment of posterior heel pain associated with calcaneal apophysitis Sever s disease Ankle joint sprains in children and evaluating the outcome of therapy Prospective Comparison of Hind Foot Stabilization Procedures in Children Study to assess the efficacy of orthotic therapy in treatment of patients with a range of musculoskeletal Orthopaedic foot and ankle conditions Examples of conditions for which the OxAFQ C has been used include Juvenile inflammatory arthritis Diagnoses Pes plano valgus Benign joint hypermobility Congenital Talipes Equino Varus Tarsal coalitions Pes cavus Metatarsus varus Hallux abducto varus bunion Toe deformity Osteochondrosis apophysitis Idiopathic toe walking Hereditary Motor Sensory Neuropathy Cerebral Palsy Down syndrome Marfan Syndrome Fractures Scoring System Details of the scoring system for the OxAFQ C can be downloaded in Dossier Extracts section Development The OxAFQ C was developed and tested in a 3 step process Phase 1 Understanding the patient s experience of their condition through qualified research Focus groups were convened with children affected by foot and ankle problems along with their parent caregiver in three age groups 5 7 8 11 and 12 15 This research resulted in themes that children felt were important and affected them Consistent themes identified by all groups were Physical Symptoms activity limitations reduced participation in certain contexts and self consciousness due to appearance and other people s attitudes The results formed the basis of the PRO Phase 2 Evaluation of test version in order to develop scales Initially 28 items were proposed 25 from Phase 1 and 3 extra from clinicians Item responses were rated on a five point scale indicating how frequently the issue affects the child from never score 4 to always score 0 A survey of 158 children and their parents was carried out to determine the scaling reliability and validity of the instrument Exploratory factor

    Original URL path: http://isis-innovation.com/outcome-measures/the-oxford-ankle-foot-questionnaire-for-children-oxafq-c/ (2016-05-01)
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  • The Oxford Elbow Score (OES) - Isis Innovation
    of Development Our Ventures Meet the CEOs Find your CEO match Incubator Team Contact For University Members Consulting Services Support FAQs Register as a consultant Commercialising Your Technology IP patents and licences Starting a company FAQs Isis Startup Incubator Oxford University Hospital NHS Foundation Trust Translational Funding University Hot Desks For Medical Sciences Researchers Contact Us News Events Publications News Events Request further information Technology Showcase 2016 Success Stories Publications Annual Reports Innovation Insights Isis newsletters Comment opinion Other publications reports Home Health outcome measures Clinical Outcomes Assessments The Oxford Elbow Score OES Share this The Oxford Elbow Score OES The Oxford Elbow Score OES is a short 12 item PRO specifically designed and developed for assessing outcomes of elbow surgery Background The PRO was designed and developed by researchers within the Health Services Research unit part of the Nuffield Department of Population Health at the University of Oxford in association with surgical colleagues at the Nuffield Orthopaedic Centre The OES which is the only patient reported PRO for elbow surgery in existence has been tested in a surgical context with patients and shown to be reliable valid and responsive Properties of the Oxford Elbow Score include A condition specific PRO designed and developed specifically for use in assessing the outcome of surgical intervention of the elbow Can be used as an indicator for recovery and general improvement in quality of life following surgery on the elbow Shown to be valid reliable and sensitive to change after rigorous testing Brief and easy to complete resulting in good return rates Can be completed anywhere and delivered by post making follow up of large numbers of patients much more feasible and cheaper than conducting clinical assessments Easy to interpret scores 3 subscales domains capture patient views on their elbow and the impact on quality of life Application of the OES could be extended to the assessment of other non surgical forms of therapy for example physiotherapy The PRO There are 12 questions in the Oxford Elbow Score with three unidimensional domains Elbow function Pain Social psychological Each of the domains comprises 4 items with good measurement properties Each of the domains sub scales was identified by Factor analysis and shown to be unidimensional by Rasch analysis In addition each scale has been demonstrated to have good internal reliability using Cronbach s alpha Example Studies The OES is primarily used to assess outcomes of elbow surgery including total elbow replacement and arthroscopic surgery Other uses of the OES include Assessment of patient outcomes following alternative non surgical interventions including physical therapy cortisone injections joint supplements and anti inflammatory medications Orthopaedic products companies have used the OES to optimise their products and associated surgical procedures in order to improve patient outcomes from surgeries employing their products Public and private healthcare providers have used the OES to assess patient outcomes across multiple facilities as a measure of the performance of individual treatment centres which can be used to identify high performing centres and to raise

    Original URL path: http://isis-innovation.com/outcome-measures/the-oxford-elbow-score-oes/ (2016-05-01)
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  • The Oxford Shoulder Instability Score (OSIS) - Isis Innovation
    Inspired Works Contact us Incubator News Incubator Services Stages of Development Our Ventures Meet the CEOs Find your CEO match Incubator Team Contact For University Members Consulting Services Support FAQs Register as a consultant Commercialising Your Technology IP patents and licences Starting a company FAQs Isis Startup Incubator Oxford University Hospital NHS Foundation Trust Translational Funding University Hot Desks For Medical Sciences Researchers Contact Us News Events Publications News Events Request further information Technology Showcase 2016 Success Stories Publications Annual Reports Innovation Insights Isis newsletters Comment opinion Other publications reports Home Health outcome measures Clinical Outcomes Assessments The Oxford Shoulder Instability Score OSIS Share this The Oxford Shoulder Instability Score OSIS The Oxford Shoulder Instability Score OSIS is a short 12 item condition specific patient reported outcome PRO measure developed and validated for measuring surgical and non surgical therapeutic outcomes of patients presenting with unidirectional or multi directional instability of the shoulder Background The OSIS is short practical reliable valid and sensitive to changes of clinical importance Some of the attributes of the OSIS are Short The OSIS is a 12 item uncomplicated questionnaire It therefore benefits from high completion rates The OSIS is easy to deploy across diverse healthcare applications Reliable Published results see development paper on patient groups demonstrate the reproducibility and internal consistency of the score Valid The OSIS has been shown to correlate well with existing related clinical and generic PRO measures Sensitive to change Effect size for the OSIS is large and results see development paper clearly show it outperforms generic PROs including those with a physical role dimension Practical Easy to complete and can be given to the patient at clinic or sent by post The PRO The OSIS is a patient self completion PRO measure containing 12 questions on activities of daily living particularly relevant to patients exhibiting shoulder instability The OSIS has been specifically designed to assess outcome of therapy both surgical and non surgical by measuring activities of daily living and pain of patients exhibiting shoulder instability Scoring System Details of the scoring system for the OKS can be downloaded in Dossier Extracts section Development During the development of the Oxford Shoulder Score it became clear that patients presenting with persistent dislocation or subluxation of the shoulder were a distinct group whose condition was usually characterised by anticipation of problems arising in relation to specific activities rather than pain This group required a specific outcome measure of its own which led to the development of the OSIS The OSIS was developed using a multi stage process consistent with industry best practice methods The OSIS joins a portfolio of well regarded and widely used orthopaedic PRO measures created by Dr Jill Dawson at the Health Services Research Unit HSRU in association with colleagues at the Nuffield Department of Population Health and the Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences NDORMS at the University of Oxford The development of the OSIS was supported by world leading clinicians at the NDORMS led by

    Original URL path: http://isis-innovation.com/outcome-measures/oxford-shoulder-instability-score-osis/ (2016-05-01)
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