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  • Jobs | oncgnostics GmbH
    Contact Press Jobs News Blog Search Jobs at oncgnostics We always welcome applications of highly motivated individuals who are interested in the concepts of oncgnostics If interested please contact us using our contact form and we will let you know about job vacancies Currently we don t have open positions for master or bachelor theses From October 2016 you can send an application document to kontakt at oncgnostics com again About us Management Advisory board Lab team History Pipeline Ovarian cancer Head and neck cancer Press Contact Access Jobs Recent Posts Greiner Bio One starts international marketing of the cervical cancer triage test GynTect oncgnostics and Greiner Bio One Diagnostics sign Partnership Agreement Fast and reliable results in cancer diagnostics Biotech startup oncgnostics receives CE mark for cervical cancer test GynTect Stay informed Enter your email address to subscribe to this blog and receive notifications of new posts by email Enter your Email Adress Our Topics GynTect Cervical cancer Information for patients Information for physicians Information for diagnostic laboratories Investors contact Recent Posts Greiner Bio One starts international marketing of the cervical cancer triage test GynTect oncgnostics and Greiner Bio One Diagnostics sign Partnership Agreement Fast and reliable results in

    Original URL path: http://www.oncgnostics.com/about-oncgnostics/jobs/?lang=en (2016-02-15)
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  • FAQ | oncgnostics GmbH
    51 52 56 58 are detected in 99 7 of all cervical cancer cases In 70 of the cases HPV16 and HPV18 are detected Only women with long term infection with high risk HPV and subsequent cervical lesions have a risk of developing precancerous lesions and cancer It is well established nowadays that HPV infection ist he main risk factor for the development of cervical cancer How can I get to know if I am infected with HPV HPV tests are used in order to detect an infection If the HPV test yields a negative result a precancerous lesion or even cancer can be excluded with 99 probability Only such a negative result is of high value for the patient Only a small part of the women infected with HPV will develop a cervical disease That s why we have developed GynTect which detects markers specifically occurring in precancerous and cancer cells How can I minimize the risk of getting infected with HPV The only way to minimize the risk of getting infected by HPV is sexual abstinence Condoms offer rather good protection since HPV like other sexually transmitted diseases are transferred through exchange of body fluids It is recommended to get immunized against the two most important cancer causing strains HPV16 and HPV18 as early as possible the German STIKO now recommends immunization from the age of 9 13 But even if immunized you should continue participating in screening programs How high is the probability to get infected with HPV Genital HPV infections occur very frequently In fact human papillomaviruses are the most frequently sexually transmitted infectous agents HPV are mainly but not exclusively transmitted sexually It is estimated that the probability to get infected with HPV ranges between 75 and 90 for both men and women For whom have we developed GynTect According to the already performed trials GynTect is suitable for all women who want to get further clarification after an abnormal Pap smear and or a positive HPV test if surgery is already required or if a watchful waiting strategy could demonstrate if an HPV infection and a tissue abnormality may heal without treatment What does a positive GynTect result mean Results obtained during clinical trials indicate that upon a positive GynTect test result a severe cervical lesion a so called CIN3 or even a cervical carcinoma from a low grade CIN1 or CIN2 may develop or already be present Invasive diagnostics colposcopy and if required biopsy both in a specialized colposcopy clinic should be performed after a positive GynTect test result During this examination conspicuous surface of the cervix should be examined very thoroughly and biopsies taken during this examination should be diagnosed by histopathology In case of a negative test result a precancerous leson or cancer can almost be excluded We recommend a re examination after 6 months with HPV testing performed first How can GynTect improve cervical cancer screening GynTect is a reliable molecular test that may clarify if a patient with unclear

    Original URL path: http://www.oncgnostics.com/faq/?lang=en (2016-02-15)
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  • Contact | oncgnostics GmbH
    Jena Germany Phone 49 0 3641 508456 Fax 49 0 3641 508451 Email kontakt at oncgnostics com Internet www oncgnostics com Arriving via Deutschen Bahn Arriving at the train station Jena West walk to the bus station Magdelstieg and take one of the lines 10 12 or 13 for 5 stops to Beutenberg Campus time ca 7 min The office of oncgnostics is located in Modul 2 level 2 of the black building directly above the bus station Arriving at the train station Paradies Bahnhof cross the road Knebelstraße and follow the road Am Volksbad Turn left into Grietgasse and walk until Holzmarkt Here turn left into the road Teichgraben where you ll find the bus stops for the lines 10 12 or 13 5 minutes walk Take one of the lines 10 12 or 13 for 6 stops to Beutenberg Campus time ca 10 min The office of oncgnostics is located in Modul 2 level 2 of the black building directly above the bus station Arriving by car Coming from the A4 take the exit Jena Göschwitz and follow the signs to Jena city center Getting to the traffic lights after passing the LIDL right hand side turn left Follow the road until you reach a whitely covered building on the right Turn left at the oposite of this building Hans Knöll Strasse Directly on the right side there is a car park with a barrier Call oncgnostics at the barrier using the pin codes shown there and park on one of the parking lots for visitors The office of oncgnostics is located in Modul 2 level 2 of the black building directly above the parking Our Topics GynTect Cervical cancer Information for patients Information for physicians Information for diagnostic laboratories Investors contact Recent Posts Greiner Bio One starts

    Original URL path: http://www.oncgnostics.com/about-oncgnostics/contact/?lang=en (2016-02-15)
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  • Access | oncgnostics GmbH
    Arriving by car Coming from the A4 take the exit Jena Göschwitz and follow the signs to Jena city center Getting to the traffic lights after passing the LIDL right hand side turn left Follow the road until you reach a whitely covered building on the right Turn left at the oposite of this building Hans Knöll Strasse Directly on the right side there is a car park with a barrier Call oncgnostics at the barrier using the pin codes shown there and park on one of the parking lots for visitors The office of oncgnostics is located in Modul 2 level 2 of the black building directly above the parking Arriving via Deutsche Bahn Arriving at the train station Jena West walk to the bus station Magdelstieg and take one of the lines 10 12 or 13 for 5 stops to Beutenberg Campus time ca 7 min The office of oncgnostics is located in Modul 2 level 2 of the black building directly above the bus station Arriving at the train station Paradies Bahnhof cross the road Knebelstraße and follow the road Am Volksbad Turn left into Grietgasse and walk until Holzmarkt Here turn left into the road Teichgraben where you ll find the bus stops for the lines 10 12 or 13 5 minutes walk Take one of the lines 10 12 or 13 for 6 stops to Beutenberg Campus time ca 10 min The office of oncgnostics is located in Modul 2 level 2 of the black building directly above the bus station oncgnostics GmbH BioInstrumentezentrum Jena Winzerlaer Str 2 07745 Jena Germany Phone 49 0 3641 508456 Fax 49 0 3641 508451 Our Topics GynTect Cervical cancer Information for patients Information for physicians Information for diagnostic laboratories Investors contact Recent Posts Greiner Bio One starts international

    Original URL path: http://www.oncgnostics.com/about-oncgnostics/access/?lang=en (2016-02-15)
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  • GynTect & Cervical cancer | oncgnostics GmbH
    or Pap IIID may lead to uncertainty in women do I get cancer Do I need surgery An HPV test may reduce the uncertainty for some of these women in case of a negative result the probability for cancer is very low A positive test result however also only in few cases indicates a precancerous lesion or cancer GynTect may provide clarity For patients Cervical cancer is still among the most frequent cancers in women worldwide Cervical cancer is however very well treatable because the disease develops very slowly For gynecologists In Germany more than 200 000 women receive a Pap smear cytology result Pap III or Pap IIID Triage by HPV testing can only reduce uncertainty for those women tested negative Patients with abnormal Pap smear and positive HPV test want clarification For diagnostic laboratories With GynTect we provide a molecular test on the basis of epigenetic markers which allows the triage of patients with abnormal Pap smear and subsequent positive HPV test result Information for patients Cervical cancer Cervical cancer diagnostics What is GynTect doing More information Contact FAQ patients Information for physicians GynTect test procedure Screening algorithm Trial data FAQ physicians Order Information for diagnostic laboratories Test principle Screening algorithm Trial data FAQ Labs Order Recent Posts Greiner Bio One starts international marketing of the cervical cancer triage test GynTect oncgnostics and Greiner Bio One Diagnostics sign Partnership Agreement Fast and reliable results in cancer diagnostics Biotech startup oncgnostics receives CE mark for cervical cancer test GynTect Stay informed Enter your email address to subscribe to this blog and receive notifications of new posts by email Enter your Email Adress Our Topics GynTect Cervical cancer Information for patients Information for physicians Information for diagnostic laboratories Investors contact Recent Posts Greiner Bio One starts international marketing of the

    Original URL path: http://www.oncgnostics.com/gyntect-cervical-cancer/?lang=en (2016-02-15)
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  • Information for patients | oncgnostics GmbH
    women in Germany get an abnormal result mainly Pap III and Pap IIID annually Many of the cellular neoplasias evoking these abnormal Pap smear diagnoses heal however spontaneously Testing for human papillomaviruses causative agents oft he cancer does not yield clarification either most women infected with HPV clear the infection even if Pap III or Pap IIID is diagnosed Surgery of these tissue neoplasias therefore often is not required especially in the light of adverse effects such as higher risk for perinatal death or preterm birth With GynTect we have developed a test that may support therapy decision and thus reduce insecurity Information for patients Cervical cancer Cervical cancer diagnostics What is GynTect doing More information Contact FAQ patients Information for physicians GynTect test procedure Screening algorithm Trial data FAQ physicians Order Information for diagnostic laboratories Test principle Screening algorithm Trial data FAQ Labs Order Recent Posts Greiner Bio One starts international marketing of the cervical cancer triage test GynTect oncgnostics and Greiner Bio One Diagnostics sign Partnership Agreement Fast and reliable results in cancer diagnostics Biotech startup oncgnostics receives CE mark for cervical cancer test GynTect Stay informed Enter your email address to subscribe to this blog and receive

    Original URL path: http://www.oncgnostics.com/gyntect-cervical-cancer/information-for-patients/?lang=en (2016-02-15)
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  • Cervical cancer | oncgnostics GmbH
    alsmost always is evoked by infection with so called human papillomaviruses HPV HPV infecten is supposed to be the the most common sexually transmitted infection In most cases the infection does not cause any symptoms and it is cleared within 1 2 years More than 150 HPV types are characterized to date 14 of these are high risk types since persistent infection with any of these types may lead to cancer Since 2007 vaccinations are available against the two HPV types which are most frequently found in cervical cancer tissue Therefore participation in screening programs is still required The so called transformation zone is located at the portio and cervix In case of small lesions HPV may enter the cells and persist From HPV infection to cancer a rare event It may take many years from infection with HPV to carcinogenesis Therefore the chance to detect the cancer or it s precursors early enough is quite high Cervical cancer develops slowly and several precancerous stages so called dysplasias or neoplasias can be diagnosed However only few of these dysplasias progress to cancer most of them heal spontaneously GynTect offers the chance to detect those dysplasias that have a high potential to progress to cancer In all other cases a strategy of watchful waiting may help to avoid surgery This is of prime importance especially for women in their reproductive age complications during pregnancy such as higher risk for preterm birth or even perinatal death may be a consequence of surgery Cellular changes during carcinogenesis In early stages only few neoplastic cells are found in the basal cell layer whereas in later stages such as CIN3 or carcinoma in situ all cell layers are affected Information for patients Cervical cancer Cervical cancer diagnostics What is GynTect doing More information Contact FAQ

    Original URL path: http://www.oncgnostics.com/gyntect-cervical-cancer/information-for-patients/cervical-cancer/?lang=en (2016-02-15)
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  • Cervical cancer diagnostics | oncgnostics GmbH
    diseases The quality of the results of this Pap smear invented by the physician George Papanicolaou largely depends upon the experience of the cytology laboratory Therefore the results are not always reliable Quite frequently the Pap smear yields a result Pap III or Pap IIID which does not unequivocally indicate cancer Most dysplasias causing such a Pap smear result do heal spontaneously Microscopy of Pap smears from a healthy patient left and a patient with severe dysplasia right Only in few cases cancer cells are visible Detection of papillomaviruses HPV tests For triage testing for the presence of the human Papillomaviruses causing cervical cancer may be performed Especially in the case of abnormal Pap smear results HPV tests may contribute to further clarification These tests are like the Pap test also made from a cervical smear In case of a negative HPV test result a precancerous lesion or cancer can be excluded even if the Pap smear result was abnormal A positive HPV test however does not contribute to clarification since in most of these cases the infections may clear and the lesions may heal We have developed GynTect in order to provide you with a decision support and to minimize uncertainty Information for patients Cervical cancer Cervical cancer diagnostics What is GynTect doing More information Contact FAQ patients Information for physicians GynTect test procedure Screening algorithm Trial data FAQ physicians Order Information for diagnostic laboratories Test principle Screening algorithm Trial data FAQ Labs Order Recent Posts Greiner Bio One starts international marketing of the cervical cancer triage test GynTect oncgnostics and Greiner Bio One Diagnostics sign Partnership Agreement Fast and reliable results in cancer diagnostics Biotech startup oncgnostics receives CE mark for cervical cancer test GynTect Stay informed Enter your email address to subscribe to this blog and receive

    Original URL path: http://www.oncgnostics.com/gyntect-cervical-cancer/information-for-patients/cervical-cancer-diagnostics/?lang=en (2016-02-15)
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