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  • VHL > Our services > DNA tests > Kinship, parentage and identity
    verify parentage has an accuracy rate of at least 99 5 For parentage verification DNA markers are determined with one DNA marker having two variants referred to as alleles One allele originates from the father while the other originates from the mother By accurately visualising a sufficient number of alleles it can be determined whether alleles DNA variants appear in the offspring that are not found in the supposed parents If all of the offspring s DNA variants are present in the parents the reliability of the test can be statistically established The result of a parentage or identification verification is limited to the question being asked Generally the result is based on a large number of DNA markers with the result being over 99 5 reliable when both parents DNA is included in the test The probability that a wrong parentage would not be identified is extremely low The reliability is reduced e g if the DNA of one of the parents is not included in the test or if the DNA profile of a parent must be reconstructed The reliability is also influenced by the genetic variation in the population The DNA markers that are used for verifying the parentage and for identification do not provide any information regarding characteristics such as coat colour and quality or about the presence or absence of genetic diseases Identification Some breeding animals are extremely valuable because of their external characteristics There are a number of methods available for identifying these animals such as tattoos chips and ear tags In some cases however it may be important to determine a DNA profile so that these animals can also be identified even without employing these methods This could prove necessary when the animal is stolen an ear tag is lost or a chip

    Original URL path: http://www.vhlgenetics.com/en-us/ourservices/dnatests/kinship,parentageandidentity.aspx (2016-02-12)
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  • VHL > Our services > DNA tests > Genetic diseases
    Routedescription Malle Belgium Our services DNA tests Genetic diseases Genetic diseases Science links variations in the DNA to certain diseases By mapping the differences between the DNA of healthy animals and animals that either carry or suffer from a certain genetic disease it can be determined in which gene and at what position in the gene a mutation has occurred that causes the genetic disease By comparing the symptoms of a disease with variation in DNA a reliable diagnostic test can be validated This generally results in publication of an article in a peer reviewed scientific journal These articles are often based on a single breed The availability of DNA tests to find out whether an animal carries or suffers from a genetic diseases enables breeders to use this knowledge when choosing a breeding partner for their animal s This can prevent the birth of offspring that suffer from a genetic disease and it may improve animal welfare If a DNA test result indicates that an animal is affected two copies of the mutation this fact is generally the basis for assuming that the animal will develop the genetic disease If a DNA test result indicates that an animal is no carrier of the mutation that causes the relevant disease it is not a guarantee that that animal will never develop the genetic disease in question specifically mutations that cause the same symptoms could occur in other locations in the animal s DNA Mutations that have been described and validated in one breed can also be present in other breeds Very often that fact is not published in additional scientific articles The presence of these mutations in other breeds is determined by service laboratories that perform the DNA tests Determining how reliable a certain DNA test is for a certain

    Original URL path: http://www.vhlgenetics.com/en-us/ourservices/dnatests/geneticdiseases.aspx (2016-02-12)
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  • VHL > Our services > DNA tests > Other genetic characteristics
    characteristics By mapping the differences between the DNA of animals that possess a particular characteristic and those that do not it can be determined in which gene and at what position in the gene a mutation has occurred that causes this characteristic By comparing the external characteristics with variation in DNA a reliable diagnostic test can be validated This generally results in publication of an article in a peer reviewed scientific journal These articles are often based on a single breed DNA tests for these external characteristics offer countless possibilities and applications for breeders Some examples are DNA tests for coat colours various animal species horn polled milk proteins cattle meat characteristics and susceptibility to E coli pig susceptibility to scrapie sheep hairlength cat and dog sex determination e g birds hyenas capybaras anteaters and sloths and quality gene pigeon The availability of these DNA tests enables breeders to use this knowledge and these DNA tests to improve the quality of a population or breed Mutations that have been described and validated in one breed can also be present in other breeds Very often that fact is not published in additional scientific articles The presence of these mutations in other

    Original URL path: http://www.vhlgenetics.com/en-us/ourservices/dnatests/othergeneticcharacteristics.aspx (2016-02-12)
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  • VHL > Our services > DNA tests > Combination Packages
    Haeringen Laboratorium VHL have developed Combination Packages VHL continues the policy to combine multiple DNA tests into single packages This enables and increases the possibilities to generate information about genetic parameters in a cost effective way In 2013 new sets of application specific Combination Packages have been designed All genetic diseases and characteristics are stored in the DNA VHL applies advanced DNA technology thus enabling Combination Packages of DNA tests at a very attractive price When performing two or more tests on the same sample a Combination Package may be less expensive than the combined price of individual tests In the beginning of 2013 VHL and Holbigenetics NV have initiated a collaboration regarding the Combination Packages Together with Dr Frank Coopman specialist veterinary genetics CombiBreed Combination Packages have been developed CombiBreed packages have been developed for dogs cats horses and pigs CombiBreed tests aim to offer a cost effective breed specific set of markers and aim to improve the sustainable breeding and general health of animals The majority of tests included are based on non patented markers because patented DNA markers are usually much more expensive to order CombiBreed for dogs The following CombiBreed Combination packages are available to order These tests are aimed at combination of breed specific combinations CombiBreed FCI Group 01 test code H474 CombiBreed FCI Group 02 test code H475 CombiBreed FCI Group 03 test code H476 CombiBreed FCI Group 04 test code H477 CombiBreed FCI Group 05 test code H478 CombiBreed FCI Group 06 test code H479 CombiBreed FCI Group 07 test code H480 CombiBreed FCI Group 08 test code H481 CombiBreed FCI Group 09 test code H482 CombiBreed FCI Group 10 test code H483 CombiBreed Golden Retriever test code H924 Combination Pack Coat Variation test code H469 Below is an overview provided of the

    Original URL path: http://www.vhlgenetics.com/en-us/ourservices/dnatests/combinationpackages.aspx (2016-02-12)
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  • VHL > Our services > Biobanking
    Wageningen Routedescription Malle Belgium Our services Biobanking Biobanking VHLGenetics has ample biobanking facilities available for the storage of samples and DNA assays The material stored may originate from animals plants and microorganisms and a very wide variety of sample types can be stored Clients who avail themselves of this service can store their samples and have them retrieved at any time they wish such as when research starts on developing

    Original URL path: http://www.vhlgenetics.com/en-us/ourservices/biobanking.aspx (2016-02-12)
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  • VHL > Our services > DNA-extraction
    Submitting samples Request DNA tests Payments Test results Information DNA tests Submission forms Requestform swabs bags General Conditions VHL Cookies News Contact Contactform Routedescription Wageningen Routedescription Malle Belgium Our services DNA extraction DNA extraction We can perform large scale DNA extractions for you on a variety of sample materials including the following Animals Blood EDTA or Heparine Blood FTA card Hair follicles Semen Swabs Tissues Feathers Plants Leaves Seeds Please

    Original URL path: http://www.vhlgenetics.com/en-us/ourservices/dnaextraction.aspx (2016-02-12)
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  • VHL > Our services > Customized Genotyping
    FAQ Taking samples Submitting samples Request DNA tests Payments Test results Information DNA tests Submission forms Requestform swabs bags General Conditions VHL Cookies News Contact Contactform Routedescription Wageningen Routedescription Malle Belgium Our services Customized Genotyping Customized Genotyping We can type any marker panel for plants or animals you need The marker panel can comprise either SNP markers or STR markers and we can also type panels containing both marker types Modern Kbioscience Kaspar technology and our years of experience with STR markers enable us to create dozens of solutions for flexible genotyping projects In addition to standard marker panels we can also compose virtually every personal marker panel As an externally accredited laboratory we can also support you during seasonal peaks with services such as the following Genotyping high sample volumes Genotyping samples in a very short turn around time DNA extraction Seasonal peaks can result in high volumes of samples and or tests With high volumes of small marker sets for example we offer you the opportunity to outsource this work to a qualitatively proven laboratory The extensive automation of our systems means that we can offer you surprisingly competitive rates Please refer to our website www snpexpert com

    Original URL path: http://www.vhlgenetics.com/en-us/ourservices/customizedgenotyping.aspx (2016-02-12)
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  • VHL > Our services > Marker Development&Validation
    Conditions VHL Cookies News Contact Contactform Routedescription Wageningen Routedescription Malle Belgium Our services Marker Development Validation Marker Development Validation Marker development Marker development and validation has never been so simple and efficient As a marker developer our goal is to be one of the most cost effective flexible and reliable service providers in the field We offer sequence screening and assay development for projects ranging from a few to a

    Original URL path: http://www.vhlgenetics.com/en-us/ourservices/markerdevelopmentvalidation.aspx (2016-02-12)
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